Salvestrin Estate Vineyard and Winery is located off Highway 29 in the heart of Napa Valley, just south of the town of St. Helena. It's approximately a 1-1/2 hour drive to from San Francisco.
To reach the winery from San Francisco, take the Bay Bridge to Highway 80, following the signs to Sacramento. Approximately five miles past the Carquinez Bridge, take the Highway 37-Columbus Parkway exit and turn right on Fairgrounds Drive, following it to Highway 29. Turn right on Highway 29 and travel north (through Vallejo and into Napa County) for approximately 30 miles, passing through the towns of Napa, Yountville, Oakville and Rutherford. Salvestrin is on the west (left) side of Highway 29 between El Bonita and Grayson streets, about 1/2 mile south of the town of St. Helena.
An alternative route from San Francisco is to take the Golden Gate Bridge to Highway 101 north. Take 101 north to Highway 37 East and 37 East to Highway 121 North. Take 121 North to Highway 12 East, which leads to Highway 29. Turn left on Highway 129 and proceed north as above.